Treatment of Sporadic Acute Puerperal Mastitis

نویسندگان

  • W. David Hager
  • John R. Barton
چکیده

OBJECTIVE The purposes of this study were to compare the efficacy of amoxicillin and cephradine for the treatment of sporadic acute puerperal mastitis (SAPM) and to evaluate the microbiology and clinical parameters of this infection. METHODS We conducted a prospective, randomized, single-blinded study comparing amoxicillin, 500 mg orally q 8 h for 7 days, and cephradine, 500 mg orally q 6 h for 7 days. The diagnostic criteria for SAPM included a temperature of > or =37.56 (> or =99.6) and erythema and tenderness of the breast(s). RESULTS Twenty-seven consecutive outpatients with SAPM were evaluated for admission to the study, and 25 of these were enrolled. The mean temperature at enrollment was 38.17 (100.7), with a mean WBC count of 11,440/microl. The most frequent bacterial isolates from expressed milk were Staphylococcus aureus (7), staphylococcal species (coagulase negative) (8), and alpha-hemolytic streptococci (4). There were no significant differences between the 2 antibiotic regimens in cure rate, mean days to resolution of symptoms, or recurrence within 30 days. Both of the treatment failures and 1 of the 3 recurrences within 30 days were amoxicillin-treated patients whose cultures grew S. aureus. CONCLUSIONS Oral amoxicillin and cephradine appear equally effective in the treatment of SAPM. Staphylococci were the most frequent isolates from the milk of women with mastitis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antepartum Mastitis: A Case Report

BACKGROUND Acute mastitis commonly occurs in the postpartum period. It has been reported only rarely in the antepartum period. CASE A 14-year-old patient presented at 29 weeks gestation with her symptoms and examination consistent with bilateral mastitis that had worsened over 2 months. She had evidence of systemic infection. She was treated with parenteral antibiotics and local skin care. Sh...

متن کامل

Experience and knowledge level of female health care professionals in Samsun province regarding puerperal mastitis.

OBJECTIVE Inappropriate or insufficient knowledge of health care professionals about puerperal mastitis can lead mothers to premature weaning, as well as the lack of education on proper breastfeeding. However, the importance of education regarding puerperal mastitis seems to be underestimated. MATERIAL AND METHODS From July to August 2014, 317 female health care professionals were surveyed in...

متن کامل

Bacteriological findings and clinical symptoms in relation to clinical outcome in puerperal mastitis.

Clinical symptoms, bacterial content in breast milk and treatment were recorded in 43 women in Oslo with puerperal mastitis. Patients with a favorable (n = 35) and unfavorable outcome (n = 8) (defined as abscess formation and/or symptom relief after more than 7 days) were compared. The group with unfavorable outcome was characterized by increased delay between symptoms and time for consultation...

متن کامل

Expanding Disease Spectrum Associated With Puerperal Mastitis

BACKGROUND Staphylococcus aureus and the beta-hemolytic streptococci are the commonest causes of puerperal mastitis which tends to be a localized disease process. This report describes 2 cases attributable to these bacteria that resulted in extramammary involvement and augmented morbidity. CASES Two cases of postpartum mastitis are described, one leading to necrotizing fasciitis caused by gro...

متن کامل

A lactating woman presenting with puerperal pneumococcal mastitis: a case report

INTRODUCTION Streptococcus pneumoniae is an uncommon etiologic agent in soft-tissue infections. CASE PRESENTATION We report the case of a 35-year-old Caucasian woman who presented to our facility with puerperal pneumococcal mastitis, and review the only other three cases of pneumococcal mastitis described in the medical literature. CONCLUSIONS The roles of the various pneumococcal vaccines ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Infectious Diseases in Obstetrics and Gynecology

دوره 4  شماره 

صفحات  -

تاریخ انتشار 1996